Searchable abstracts of presentations at key conferences in endocrinology

ea0010dp1 | Diabetes, metabolism and cardiovascular | SFE2005

Stimulation of insulin secretion by an aqueous extract of Gymnema sylvestre: role of intracellular calcium

Asare-Anane H , Huang G , Amiel S , Jones a P , Persaud S

ObjectivePlant-derived extracts have long been used to treat Type 2 diabetes mellitus (T2DM), but their effects have not been rigorously investigated at the cellular level in vitro. The aims of the current study were to determine the effects of a virgin isolate of Gymnema sylvestre (GS), designated OSA, on pancreatic β-cell function.Materials and MethodsCell viability was measured by Trypan...